Efficient bonding and connecting of silicone components

A process technology for creating strong and durable connections between silicone regions or parts is presented, which involves a specific combination of vacuum ultraviolet irradiation and tailored application of mechanical pressure.

Pentafluorocyclopropanation of drugs and pesticides

The evaluation of the pentafluorocyclopropyl group as a chemotype in crop protection and medicinal chemistry has been hampered in the past by the lack of suitable methodologies that enable the practical incorporation of this moiety into advanced synthetic intermediates. By synthesizing an unprecedented sulfonium salt, 5-(pentafluorocyclopropyl)-dibenzothiophenium triflate, and using it as a versatile reagent for photoinduced pentafluorocyclopropylation, a wide range of (hetero)arenes are enabled by a radical-mediated mechanism.

Biobased adhesive formulation

A novel production method for a biobased adhesive, which comprises a tailored lignin structure as main component, is presented. The process technology overcomes the use of toxic phenol and formaldehyde, while the resulting adhesive exhibits superior physicochemical and mechanical properties.

New class of Reagents for Alkynylation and Cyanation

Scientists from the University of Göttingen developed novel reagents to attach terminal C-C or C-N triple bonds to organic molecules. These novel, sulfur based reagents have two striking advantages over the widely used EBX based reagents: They do not suffer from being potentially explosive but still show high alkynylation rates with yields up to 90% and the reduced reactivity allows for selection of alkynylation sites in one molecule.

Neue in der Umwelt abbaubare Antibiotika

Wissenschaftler der Leuphana Universität Lüneburg entwickelten durch gezielte molekulare Strukturveränderungen in der Umwelt spaltbare Antibiotika auf Basis der Fluorchinolone. Dadurch kann die Umwelt-Abbaubarkeit verbessert werden und erreicht werden, dass die Antibiotika rasch nach der Anwendung inaktiviert werden. Die vorliegende Erfindung ermöglicht somit eine Balance zwischen Abbaubarkeit in der Umwelt und ausreichender Stabilität und Wirksamkeit in der Therapie.