Dopamine producing organoids for therapy of Parkinson’s Disease
Researchers at the University Medical Center in Göttingen, Germany, have developed a method to produce special brain organoids called „dopamine-producing neuronal organoids“ (d-NOs). These organoids have been shown to release dopamine at levels that are effective for biological processes. This method is ideal for the production of an advanced therapy medicinal tissue-engineered product (ATMP-TEP) for clinical use in Parkinson’s disease. Furthermore, the invention provides a method for producing d-NOs for use in disease modelling, drug screening and drug development.
OAD – Smart Defibrillation: Adaptive Energy. Personalized shocks. Improved outcomes.
Every second counts — and every shock matters. Optimized Amplitude Defibrilation (OAD) personalizes defibrillation in real time, protecting the heart and giving patients a better chance of survival. A smart upgrade for every defibrillator, where precision meets compassion.
Membrane or implant that mimic healthy subchondral bone microarchitecture for treating joint-related diseases
Scientist at the University Medicine Göttingen, Germany developed a method for determining the health-state of a joint (e.g. in osteoarthritis) by analyzing subchondral bone microarchitecture. The invention not only allows diagnosis, but also the design of a biocompatible membrane and/or an implant for the replacement and finally regeneration of damaged subchondral bone allowing regeneration of cartilage and joint function.