Self-Healing Bio-Based Adhesive System for Circular Bonding Applications
This technology is a formaldehyde-free, bio-based adhesive for wood and similar materials that can self-heal damage by heating and cooling, using reversible Diels-Alder chemistry for easy repair, recycling, and sustainable industrial use.
Synchronized Multi-Parameter Measurement of Contractile Cardiac Tissues for Drug Screening
This technology is a three‑modal platform that simultaneously measures calcium signals, electrical activity, and contractile force in engineered heart tissue. A shared timing system ensures precise alignment, enabling detailed analysis for cardiac drug testing and disease modeling.
Novel small molecule HDAC-inhibitor: potential game changer to fight immune evasive cancers
A novel Inhibitor binding to a specific HDAC molecule reduces the ability of tumors to hide from the immune system and increases the ability of immune cells to attack tumors. This might widen the use of promising Antibody based tumor therapies also to those cancer types, where tumors evade from the immune system.
ADSYNX – Adaptive Control Method for Signal Synchronization
The ADSYNX technology provides a fast and adaptive method for the synchronization of different signals (skew compensation) for any electrical or optical system up to the GHz regime.
TomoSTED – faster STED imaging at lower light doses
Tomographic STED (TomoSTED) uses a rotating 1D depletion pattern instead of the classical 2D donut shaped STED-beam. The reduction from 2D to 1D depletion results in a more robust depletion with a favourable light intensity distribution pattern, which allows to significantly reduce the overall light dose while simultaneously increasing the signal to noise ratio. Thus TomoSTED allows faster imaging while causing less bleaching while maintaining image quality.
Reducing the mortality rate of patients after Aortic-Valve Implantation by Anti-Fibrotic Treatment
A subpopulation of patients with a very high risk to die in only one year after an aortic valve implantation (AVI) was identified. A novel, anti-fibrotic treatment was developed, which adresses the most important factor for the survival rate of patients and is being tested in a phase 3 clinical trial.
Fast deconvolution of 3D Light-Sheet-Images
VALID combines theoretical considerations and the usage of empiric image data to alculate the true dimensions of the a light sheet. This allows to deconvolve a 3D image stack by a precise subtraction of the bleed-through signal between the single slices at each position of the light sheet in 3D. Furthermore, VALID extracts information allowing to define the optimal distaince between the single slices during imaging, which reduces data size and speeds up imaging itself, as well as all subsequent image processing. This approach is surperior to known deconvolutuion methods, which are either made for pointwise (e.g. confocal) imaging or use crude estimations for the 3D shape of the lightsheet.
Multi Target Drugs for treatment of Heart Failure by stabilization of Ca2+ levels
Novel Multi-Target drugs, which can modulate two key players of the Ca2+ housekeeping in heart muscle cells were jointly developed at the University Medical Center Göttingen and the MPI-NAT. The substances show increased efficiency over comparable single target RyCal drugs, which are currently under investigation in clinical trials.
RoboBalloon
RoboBalloon is a helium ballon than can autonomously move along the ceiling – without any special infrastructure. It can be equipped with for example sensors, lights or loud speakers.
Carbon PreForm – Formation of the SEI layer on graphite in an external electrochemical cell
Carbon PreForm – Formation of the SEI layer on graphite in an external electrochemical cell Lithium-ion batteries represent the decisive component with regard to electromobility. Their electrical parameters significantly determine the range and performance of the electric vehicles. The present patented technology enables a process for preparing the anode material before producing the actual battery. […]