Antibodies for Licensing
Antibodies for Licensing Antibodies for Licensing Scientists at the Georg-August-University Göttingen generated many different monoclonal antibodies. We are looking for companies, who are interested in licensing these antibodies for selling them to industrial and scientific institutions or for developing advanced diagnostic tests and therapeutic solutions. This unique collection comprises the listed clones: Overview available clones […]
Mouse model for arthritic diseases
An new KO mouse model for chondropathies and arthritis-related diseases to study dysfunction of chondrocytes.
Ordering Algae from the Culture Collection of Algae
Ordering Algae from the Culture Collection of Algae Micrasterias radiata (SAG 161.80) Bildquelle: SAG The Culture Collection of Algae at the Georg-August-University Göttingen is one of the world’s largest collections of living microscopic algae. Founded in 1954, the SAG collection today comprises around 2.250 strains (representing ca. 521 genera and 1202 species) from almost all evolutionary lineages […]
Animal model for Gastrointestinal Stromal Tumor (GIST)
Gastrointestinal stromal tumor (GIST) is one of the most common mesenchymal tumors of the gastrointestinal tract. GISTs occur in 10-20 per one million people. Thus, GIST has been named as an orphan drug disease. Scientists at the University of Göttingen developed a new animal drug screening model for GIST, which is caused by dysfunction of the Hedgehog pathway.
Animal model for sporadic Alzheimer’s Disease
Scientists of the University of Göttingen developed a transgenic mouse model for sporadic Alzheimer’s Disease (tg4-42 = TBA83). This is the first mouse model without any mutations showing neurological deficits by transgenic over-expressing a major form of amyloid beta peptides (N-truncated Abeta 4-42) found in the brain of AD patients. Abeta 4-42 was the first peptide discovered in AD-typical plaques in 1986. The neurological phenotype resembles that of mouse models with neurodegeneration in the hippocampus.
Monoclonal antibodies against biotinylable AP-tag / Avitag
Monoclonal antibodies against biotinylable AP-tag / Avitag Chemokine receptors undergo internalization and desensitization in response to ligand activation. Internalized receptors are either preferentially directed towards recycling pathways (e.g. CCR5) or sorted for proteasomal degradation (e.g. CXCR4). Scientists at the Georg-August-University Göttingen developed a method monoclonal antibody against a biotinylable peptid (Epitope-Tag) called AP-tag or Avi […]