Dual Target Drugs for treatment of Heart Failure

Written by Dr. Martin Andresen on 21 June 2022.

Multi Target drugs stabilize Ca2+ levels improving heart functioning

Newly developed drugs stabilize the Ca2+ level in heart muscle cells and can prevent heart failure. These novel drug-candidates allow a simultaneous modulation of the function of the two transporters RyR2 and SERCA, which have key roles in the Ca2+ housekeeping and signaling pathway.