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About us

MBM ScienceBridge GmbH evaluates, protects and commercializes inventions of higher education institutions and research facilities. It was founded as a private company and wholly owned subsidiary of the University of Göttingen Public Law Foundation in 2004.

We see our mission in the motivation of scientists to also look at their own research results from the perspective of an economically relevant invention and to report such to the employer as an employee invention.

In the case of promising inventions, we coordinate the application for an intellectual property right with external patent lawyers who are specialised in the relevant field

We subsequently present such inventions worldwide to companies in order to identify partners who are interested in developing the invention into a product and placing the product onto the market

Prevention and Treatment of Mastitis with Probiotics

Mastitis continues to be the most important economic risk for dairy farmers, accounting for about 40% of the total direct costs of the common production diseases. This technology is a biological approach to mastitis prevention based on a special combination of probiotic bacteria, leading to a protection against  the majority of pathogenic bacteria for mastitis.

Challenge

Current treatment, both for prophylaxis and therapy, rely heavily on antibiotics, which is costly and frequently ineffective due to the overuse of antibiotics in veterinary medicine resulting in antibiotic resistance. Recent legislation in the EU are restricting the use of antibiotics in animals leading to greater controls and limitations in their use. Thus, there is an unmet need for alternative therapies.

Our Solution

Scientists at the University of Applied Sciences and Arts Hannover developed a probiotic teat dip as an active way to protect the teat ends against pathogenic bacteria. The special formulation is based on a combination of non-pathogenic probiotic bacteria, which protects the teats against major pathogens of mastitis.

Source: J-H. Paduch

Advantages

  • Combination of probiotic non-pathogenic bacteria for more effective protection against majority of pathogenic bacteria for mastitis.
  • Probiotics actively colonize teats to form a protective barrier.
  • Special formulation as teat dip with prolonged survival of probiotic bacteria.
  • Showed significant reduction of pathogens as well as of somatic cell counts in an initial field test.
  • Showed significant reduction of mastitis cases on hifers in an initial field test.
  • Probiotic bacteria can be produced cheaply and in large quantities.
  • Probiotic foodgrade organism with GRAS status, hence no withholding periods for the milk as in the case of treatment with antibiotics = no milk losses!

Applications

  • Natural, effective alternative to antibiotic therapy for prevention and treatment of mastitis.
  • Can be applied as teat dip or other formulations.
  • Particularly effective during the dry period.

Developmental Status

In vitro and in vivo proof of concept in a first dairy farm field study.

Patent Status

A European patent has been granted and validated in DE, FR, GB (Patent owner: University of Applied Sciences and Arts Hannover).

References

EP3004399B1

Contact

Dr. Stefan Uhle
Patent Manager Life Science
E-Mail: suhle(at)sciencebridge.de
Tel: +49 551 30724 154
Referenz: BioC-1553-HsH

Tags: Therapy

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MBM ScienceBridge GmbH supports scientists, evaluates inventions, oversees applications for intellectual property rights and out-licenses patents of universities and research institutions in Göttingen and Lower Saxony.

Our company evaluates, protects and commercializes inventions of higher education institutions and research facilities. It was founded as a private company and wholly owned subsidiary of the University of Göttingen, Public Law Foundation, in 2004.


Office of MBM ScienceBridge GmbH:
The office of the MBM ScienceBridge GmbH resides in the Laser Laboratory on the northern campus of the Georg-August-University Göttingen.

A subsidiary of

Georg-August-Universität Göttingen