Pan-Coronavirus Therapy - viral genome disruption with Cas13

Pan-Coronavirus Therapy

Pan-Coronavirus Therapy using a Cas13-guideRNA system. The antiviral effect is based on an Cas13-guideRNA-AAV vector with up to five guideRNAs, which target and disrupt the genome of the Coronavirus - blocking viral replication. A therapeutic effect was proven in vivo in the SARS-CoV2 Hamster Model.

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Georg-August-Universität Göttingen