Dopamine producing organoids for therapy of Parkinson’s Disease
This invention describes a robust and versatile method for producing brain organoids that release dopamine at levels suitable for clinical use in Parkinson's disease. It also provides brain organoids for disease modelling, drug screening and drug development.
Membrane or implant that mimic healthy subchondral bone microarchitecture for treating joint-related diseases
The present invention lies in the field of diagnosing and treating joint-related diseases. It provides for a membrane and an implant that mimic the healthy subchondral bone microarchitecture allowing for the regeneration of the joint’s bony and cartilaginous structures as well as its functionality.