Light Sheet Imaging

Dynamic Microconfiner: Biomimetic 3D cell culture

Dynamic Microconfiner Microconfiner allows 2D cell culture mimicking 3D conditions in living organisms

A novel Micronfiner for the first time allows to create a topological, mechanical and chemical controlled cell culture system for reproducible bio-mimetic culture conditions.

 

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New approach for Ligh-Sheet-Deconvolution

Fast deconvolution of 3D Ligh-Sheet Images (VALID)

Vertical Algebraic LIght sheet Deconvolution (VALID) combines theoretical considerations and the usage of empiric image data for deconvolving 3D image stacks. By using an iterative approach, VALID is able calculate the true dimensions of a light sheet, which allows to precisely subtract bleed-through signal between the single slices - at each position of the light sheet in 3D.

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Georg-August-Universität Göttingen